Energy is inherent to all the characteristics that contribute to the biological definition of life. Energy imposes an endless cycle, a process that must be followed to continue to act and live. From birth to death, one must feed, grow, combat threats from the environment, adapt, reproduce. All forms of life are confronted with the same conditions for the possibility of life. One might think that energy produces forms, flows, and deep structures that are found wherever it is needed. In this sense, it could be likened to the idea of Urpflantz developed by Goethe, which designates the generative principle, the scheme from which all forms of a species stem. In our contribution, we hypothesize that energy is isomorphante and that its semiotic study would help enrich the understanding of life as a meaningful effect. Nevertheless, we will need to overcome the barriers posed by formal structuralism. Indeed, according to Denis Bertrand, Greimas rejected the concepts of "energy" and "dynamism" since they describe physical phenomena that do not have a foothold in the relevance plan of formalism. Drawing inspiration from Goethe's morphological theory and the morphodynamic structuralism of Lévi-Strauss, as taken up by Jean Petitot, we will see that transformation is induced by energetic stakes. We believe that reintroducing the semiotic question of energy to the table can enable us to contribute to the construction of a semiotics, not only as a science of man, but as a science of nature (Marrone, 2017).