It is about synthesizing a semiotic investigation on the literary work “Do androids dream of electric sheep?” by P.K. Dick (1968). The description gives us an account of a complex structuring following Umberto Eco (1981). The author, faced with the industrial production of synthetic humans, proposes in the world of the novel, an operation of generating the distinctive features of the human, thus developing two models. budget reader: android and human; model readers that fail to crystallize into an interpretive model of differentiabilities. In short, the text is located in an empty space, full of phobic signifiers. Following Peirce, the author's unconscious develops into firstities (signifiers) that he wants to focus on as indications of some differentiability between the human and the synthetic human (secondness), but he fails to constitute the two models he would like: the reader, model of the human. and that of the synthetic. This leads to The phobia is linked to a fear that appears due to the unclear transformation of symptoms into solid analytical schemes, a rational thirdness. Hence, the analytical deterritorialization, the absence of a place from which to speak and interpret. In short, this emptiness is also that of the author who would like to place himself above what he is, to make himself invisible, nowhere is the real subject of the author, he who can only be a product of the historical process, very different from “Jean of Saintré by Antoine de la Salle”, described by Julia Kristeva in 1970.