The research examines how the concept of Earthships are a type of contemporary techno-living space that functions as a self-sustainable potentiality for its inhabitants through the integration of repurposed commodities and natural local resources, this offers a trajectory of co-development with the environment and a creative evolutionary process of Farouk Seif’s (2019) concept of de-sign. This research identifies how the object(s) (Earthship and materials used), the subject(s) (creator and inhabitant) and the environment (physical and hyperreal) are interrelated during the process of co-development by utilizing the systems offered by nature and culture. What we will see is that the trajective process of an inhabitant aiming for “off-the-grid” living within a sustainable environment requires vital resources that are understood and provided from biological, cultural, technological, political, and ecological systems. Within this framework, the concept of de-sign is a metatheory that bridges how nature is a continuously unfolding, evolving system which incorporates our theoretical understanding of political ecology, semiotic ecology, semiotic components, and the mesological process which are all interwoven that forms a trajectory by the relations of the inhabitants’ lifeworld and the space inhabited. Through the dynamic interweaving of these juxtaposed lenses, one can argue that a new branch of semiotics emerges, mesosemiotics, which has the goal to find the middle ground for the continuous unfolding meaning that emerges within the inseparability of nature and culture.